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Article

Associations between polymorphisms in the mitochondrial uncoupling proteins (UCPs) with T2DM.

Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2008

Lee Hye-Ja, Ryu Ha-Jung, Shin Hyoung-Doo, Park Byung Lae, Kim Jong Yeol, Cho Young Min, Park Kyong Soo, Song Jihyun, Oh Bermseok

Abstract excerpt

BACKGROUND: Mitochondrial uncoupling proteins (UCPs) are considered pivotal regulators of energy and glucose homeostasis. We examined the effect of 23 single nucleotide polymorphisms (SNPs) in the UCP genes on type 2 diabetes mellitus (T2DM) and related phenotypes to identify genetic factors that may be involved in susceptibility to T2DM. METHODS: We directly sequenced the coding region, portions of the 5'- and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18755175
DOI: 10.1016/j.cca.2008.07.029

Genes

UCP2
UCP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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