The cholinergic gene locus is coordinately regulated by protein kinase A II in PC12 cells.

doi:10.1046/j.1471-4159.1998.71031118.x

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Article

The cholinergic gene locus is coordinately regulated by protein kinase A II in PC12 cells.

Journal of neurochemistry - 1 Sept 1998

Shimojo M, Wu D, Hersh L B

Abstract excerpt

The vesicular acetylcholine transporter (VAChT) gene and the choline acetyltransferase (ChAT) gene comprise the cholinergic gene locus. We have studied the coordinate regulation of these genes by cyclic AMP-dependent protein kinase (PKA) in the rat pheochromocytoma cell line PC12 and PC12 PKA-def...

Topics

Animals
Bucladesine
Carrier Proteins
Choline O-Acetyltransferase
Chromosome Mapping
Cyclic AMP-Dependent Protein Kinase Type II
Cyclic AMP-Dependent Protein Kinases
Gene Expression Regulation, Enzymologic
Isoquinolines
Membrane Transport Proteins
Mutation
PC12 Cells
Polymerase Chain Reaction
RNA, Messenger
Rats
Sulfonamides
Vesicular Acetylcholine Transport Proteins
Vesicular Transport Proteins

Source

Open in PubMed

Identifiers

PMID: 9721736
DOI: 10.1046/j.1471-4159.1998.71031118.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9721736-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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