Article
A cyclic AMP-dependent pathway regulates the expression of acetylcholinesterase during myogenic differentiation of C2C12 cells.
The Journal of biological chemistry - 27 Sept 2002
Siow Nina L, Choi Roy C Y, Cheng Anthony W M, Jiang Joy X S, Wan David C C, Zhu Shang Q, Tsim Karl W K
Abstract excerpt
The expression of acetylcholinesterase (AChE) is markedly increased during myogenic differentiation of C2C12 myoblasts to myotubes; the expression is mediated by intrinsic factor(s) during muscle differentiation. In order to analyze the molecular mechanisms regulating AChE expression during myogenic differentiation, a approximately 2.2-kb human AChE promoter tagged with a luciferase reporter gene, namely...
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