Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional identification of a vesicular acetylcholine transporter and its expression from a “cholinergic” gene locus.

1 Sept 1994

Abstract excerpt

The vesicular acetylcholine transporter (VAChT) has been identified and characterized based on the acquisition of high affinity vesamicol binding and proton-dependent, vesamicol-sensitive acetylcholine accumulation by a fibroblast cell line transfected with a clone from a rat pheochromocytoma cDNA library encoding this protein. The distribution of VAChT mRNA coincides with that reported for choline...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Synthase and ATPases Research
Share to Cholinesterase and Neurodegenerative Diseases
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8071310
DOI: 10.1016/s0021-9258(17)31734-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional identification of a vesicular acetylcholine transporter and its expression from a “cholinergic” gene locus.PMID 8071310Read ↗

The Cholinergic Gene LocusSemantic proximity Read ↗

Search for the acetylcholine and vesamicol binding sites in vesicular acetylcholine transporter: the region around the lumenal end of the transport channel.Semantic proximity Read ↗

Dileucine motif is sufficient for internalization and synaptic vesicle targeting of vesicular acetylcholine transporter.Semantic proximity Read ↗

Isolation and characterization of mutants for the vesicular acetylcholine transporter gene in Drosophila melanogaster.Semantic proximity Read ↗

The vesicular acetylcholine transporter interacts with clathrin-associated adaptor complexes AP-1 and AP-2.Semantic proximity Read ↗

Novel strains of mice deficient for the vesicular acetylcholine transporter: insights on transcriptional regulation and control of locomotor behavior.Semantic proximity Read ↗

Mutational analysis of basic residues in the rat vesicular acetylcholine transporter. Identification of a transmembrane ion pair and evidence that histidine is not involved in proton translocation.Semantic proximity Read ↗

Choline transporter mutations in severe congenital myasthenic syndrome disrupt transporter localizationSemantic proximity Read ↗

Cloning and Characterization of Human NTT5 and v7-3: Two Orphan Transporters of the Na+/Cl−-Dependent Neurotransmitter Transporter Gene FamilySemantic proximity Read ↗

Nuclear choline acetyltransferase activates transcription of a high-affinity choline transporter.Semantic proximity Read ↗

Sweat gland innervation is pioneered by sympathetic neurons expressing a cholinergic/noradrenergic co-phenotype in the mouse.Semantic proximity Read ↗

Transgenic line for the identification of cholinergic release sites in Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.