Article
Integrin-mediated signal transduction in cells lacking focal adhesion kinase p125FAK.
FEBS letters - 7 Aug 1998
Ueki K, Mimura T, Nakamoto T, Sasaki T, Aizawa S, Hirai H, Yano S, Naruse T, Nojima Y
Abstract excerpt
We have previously shown that integrin-dependent tyrosine phosphorylation of p130Cas (Cas) could be induced in a mouse fibroblast cell line that does not express focal adhesion kinase p125FAK (FAK). By analyzing FAK-deficient (FAK-/-) cells transiently expressing Cas mutant proteins, we demonstra...
Topics
- Animals
- Cell Adhesion
- Cell Adhesion Molecules
- Cells, Cultured
- Crk-Associated Substrate Protein
- Focal Adhesion Kinase 1
- Focal Adhesion Kinase 2
- Focal Adhesion Protein-Tyrosine Kinases
- Focal Dermal Hypoplasia
- Gene Expression
- Integrins
- Mice
- Mice, Mutant Strains
- Mutation
- Phosphoproteins
- Phosphorylation
- Protein-Tyrosine Kinases
- Proteins