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Article

Genetic interactions and dosage effects of Polycomb group genes in mice.

Development (Cambridge, England) - 1 Sept 1998

Bel S, Coré N, Djabali M, Kieboom K, Van der Lugt N, Alkema M J, Van Lohuizen M

Abstract excerpt

In Drosophila and mouse, Polycomb group genes are involved in the maintenance of homeotic gene expression patterns throughout development. Here we report the skeletal phenotypes of compound mutants for two Polycomb group genes bmi1 and M33. We show that mice deficient for both bmi1 and M33 present stronger homeotic transformations of the axial skeleton as compared to each single Polycomb group mutant, indicating...

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Identifiers

PMID: 9716520
DOI: 10.1242/dev.125.18.3543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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