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Article

The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression.

Mechanisms of development - 1 Aug 1996

van der Lugt N M, Alkema M, Berns A, Deschamps J

Abstract excerpt

Drosophila homeotic genes and vertebrate Hox genes are involved in the anteroposterior organization of the developing embryo. In Drosophila, the Polycomb- and trithorax-group genes are required to maintain the homeotic genes throughout development in the repressed or activated state, respectively. The murine Bmi-1 proto-oncogene was shown to exhibit homology to the Polycomb-group gene Posteior sex combs. Mice...

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PMID: 8887324
DOI: 10.1016/s0925-4773(96)00570-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression.PMID 8887324Read ↗

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