Article
The defect in the metabolism of erythritol of the Brucella abortus B19 vaccine strain is unrelated with its attenuated virulence in mice.
Vaccine - 1 Oct 1998
Sangari F J, Grilló M J, Jiménez De Bagüés M P, González-Carreró M I, García-Lobo J M, Blasco J M, Agüero J
Abstract excerpt
The role of the defect in erythritol catabolism in the attenuated virulence of Brucella abortus B19 vaccine strain in mice was investigated by means of five different strains: (i) the erythritol sensitive B19 vaccine strain; (ii) a natural erythritol tolerant (NET) mutant obtained spontaneously from B19; (iii) an erythritol resistant derivative from B19 (FJS19) obtained by gene replacement of the deleted ery...
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