Article
Identification of Brucella abortus B19 vaccine strain by the detection of DNA polymorphism at the ery locus.
Vaccine - 1 Apr 1994
Sangari F J, Agüero J
Abstract excerpt
As sensitivity to erythritol is the main feature of the Brucella abortus B19 vaccine strain, an attempt to define the genetic basis of this phenotypic trait was made in order to explore its usefulness as a means of molecular identification of strain B19. With this purpose, an erythritol-sensitive derivative of B. abortus strain 2308 was generated by Tn5 transposition methods. Restriction fragments from a cloned...
Topics
- Brucella
- Brucella Vaccine
- Brucella abortus
- DNA, Bacterial
- Drug Resistance, Microbial
- Erythritol
- Genes, Bacterial
- Phenotype
- Polymorphism, Restriction Fragment Length
- Species Specificity
- Vaccines, Attenuated