Article
Impaired antibody responses in H-2Ab mice.
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 1998
Gustavsson S, Hjulström-Chomez S, Lidström B M, Ahlborg N, Andersson R, Heyman B
Abstract excerpt
In murine in vivo systems, Ags administered in physiologic solutions together with specific IgE induce a significantly higher Ab response than Ags administered alone. In vitro, IgE in complex with Ag enhances B cell-mediated presentation of the Ag to T cells. Both phenomena require an intact low...
Topics
- Animals
- Antibody Formation
- Antigens
- Crosses, Genetic
- Dose-Response Relationship, Immunologic
- Drug Combinations
- Epitopes
- Female
- Freund's Adjuvant
- Genetic Linkage
- H-2 Antigens
- Histocompatibility Antigens Class II
- Immunoglobulin E
- Immunoglobulin G
- Injections, Intravenous
- Male
- Mice
- Mice, Inbred BALB C
