Article
Divergent regulation of the human atrial natriuretic peptide gene by c-jun and c-fos.
Molecular and cellular biology - 1 Jan 1992
Kovacic-Milivojević B, Gardner D G
Abstract excerpt
Employing transient transfection analysis in neonatal rat cardiocytes, we have demonstrated that overexpression of c-jun results in a dose-dependent induction of the human atrial natriuretic peptide (hANP) gene promoter. Studies using a series of mutations in the hANP gene promoter identified a T...
Topics
- Animals
- Animals, Newborn
- Atrial Natriuretic Factor
- Base Sequence
- Cells, Cultured
- DNA
- Gene Expression Regulation
- Humans
- Molecular Sequence Data
- Mutation
- Proto-Oncogene Proteins c-fos
- Proto-Oncogene Proteins c-jun
- Rats
- Rats, Inbred Strains
- Tetradecanoylphorbol Acetate
- Transcription, Genetic
- Transfection