Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Divergent regulation of the human atrial natriuretic peptide gene by c-jun and c-fos.

Molecular and cellular biology - 1 Jan 1992

Kovacic-Milivojević B, Gardner D G

Abstract excerpt

Employing transient transfection analysis in neonatal rat cardiocytes, we have demonstrated that overexpression of c-jun results in a dose-dependent induction of the human atrial natriuretic peptide (hANP) gene promoter. Studies using a series of mutations in the hANP gene promoter identified a TRE-like, cis-acting regulatory sequence which conferred c-jun sensitivity. This same region was shown to interact with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cells, Cultured
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Transcription, Genetic

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 1530876
DOI: 10.1128/mcb.12.1.292-301.1992
PMCID: PMC364109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Divergent regulation of the human atrial natriuretic peptide gene by c-jun and c-fos.PMID 1530876Read ↗

The C-terminal domain of c-fos is required for activation of an AP-1 site specific for jun-fos heterodimers.Semantic proximity Read ↗

Molecular regulation of the brain natriuretic peptide gene.Semantic proximity Read ↗

Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic responseSemantic proximity Read ↗

Dominant negative mutant of c-Jun inhibits cardiomyocyte hypertrophy induced by endothelin 1 and phenylephrine.Semantic proximity Read ↗

Possible role of c-Jun in transcription of the mouse renin gene.Semantic proximity Read ↗

AFos dissociates cardiac myocyte hypertrophy and expression of the pathological gene program.Semantic proximity Read ↗

Expression and regulation of the atrial natriuretic factor encoding gene during development and diseaseSemantic proximity Read ↗

Transactivation of c-fos and beta-actin genes by raf as a step in early response to transmembrane signals.Semantic proximity Read ↗

Regulation of Gene Expression by cGMP-dependent Protein KinaseSemantic proximity Read ↗

Functional dissection in vitro of the human c-fos promoter.Semantic proximity Read ↗

Modulation of MLC-2v gene expression by AP-1: complex regulatory role of Jun in cardiac myocytes.Semantic proximity Read ↗

Stimulation of atrial natriuretic factor promoter activity by Src and Ras in cultured neonatal rat ventricular myocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.