Article
cyclops encodes a nodal-related factor involved in midline signaling.
Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 1998
Rebagliati M R, Toyama R, Haffter P, Dawid I B
Abstract excerpt
Ventral structures in the central nervous system are patterned by signals emanating from the underlying mesoderm as well as originating within the neuroectoderm. Mutations in the zebrafish, Danio rerio, are proving instrumental in dissecting these midline signals. The cyclops mutation leads to a...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Body Patterning
- Central Nervous System
- DNA Primers
- DNA, Complementary
- Eye Abnormalities
- Gene Expression Regulation, Developmental
- Molecular Sequence Data
- Mutation
- Nodal Signaling Ligands
- Phenotype
- Proteins
- Signal Transduction
- Transforming Growth Factor beta
- Zebrafish