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Article

Cloning and characterization of zebrafish smad2, smad3 and smad4.

Gene - 4 Apr 2000

Dick A, Mayr T, Bauer H, Meier A, Hammerschmidt M

Abstract excerpt

smad genes encode transcription factors involved in the signal transduction of members of the TGFbeta superfamily. We report here the cloning, characterization and genomic mapping of smad2, smad3 and smad4 from the zebrafish, Danio rerio. In Xenopus, smad2 overexpression has been shown to interfere with gastrulation and dorsal cell fate specification. However, full-length zebrafish smad2, although functionally...

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PMID: 10767528
DOI: 10.1016/s0378-1119(00)00056-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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