Article
Morphopoietic determinants of HIV-1 Gag particles assembled in baculovirus-infected cells.
Virology - 1 Aug 1998
Gay B, Tournier J, Chazal N, Carrière C, Boulanger P
Abstract excerpt
The determinants for HIV-1 particle morphology were investigated using various deletion and insertion mutants of the Gap precursor protein (Gag) expressed in baculovirus-infected cells and ultrastructural analysis of membrane-enveloped Gag particles under the electron microscope. Five discrete regions were found to influence the size, the variability in dimension, and the sphericity of the particles: (i) the...
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