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Article

Assembly-defective point mutants of the human immunodeficiency virus type 1 Gag precursor phenotypically expressed in recombinant baculovirus-infected cells.

Journal of virology - 1 May 1993

Hong S S, Boulanger P

Abstract excerpt

Two substitution mutants of the human immunodeficiency virus type 1 gag gene product were isolated after nitrous acid mutagenesis of a recombinant baculovirus expressing a non-N-myristylated, p6-deleted Gag precursor (Pr49). Both mutants failed to assemble intracellular Gag virus-like particles, as does the parental recombinant, and therefore expressed a self-assembly defective (Sad) phenotype in insect cells....

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Identifiers

PMID: 8474175
DOI: 10.1128/JVI.67.5.2787-2798.1993
PMCID: PMC237603

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Source receipt: pubmed, retrieved 7 Sept 2026.

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