Article
Analysis of minimal human immunodeficiency virus type 1 gag coding sequences capable of virus-like particle assembly and release.
Journal of virology - 1 Oct 1998
Wang C T, Lai H Y, Li J J
Abstract excerpt
We have constructed a series of human immunodeficiency virus (HIV) gag mutants by progressive truncation of the gag coding sequence from the C terminus and have combined these mutants with an assembly-competent matrix domain deletion mutation (DeltaMA). By using several methods, the particle-producing capabilities of each mutant were examined. Our analysis indicated that truncated Gag precursors lacking most of...
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