Article
Mutations in the spacer peptide and adjoining sequences in Rous sarcoma virus Gag lead to tubular budding.
Journal of virology - 1 Jul 2008
Keller Paul W, Johnson Marc C, Vogt Volker M
Abstract excerpt
All orthoretroviruses encode a single structural protein, Gag, which is necessary and sufficient for the assembly and budding of enveloped virus-like particles from the cell. The Gag proteins of Rous sarcoma virus (RSV) and human immunodeficiency virus type 1 (HIV-1) contain a short spacer peptide (SP or SP1, respectively) separating the capsid (CA) and nucleocapsid (NC) domains. SP or SP1 and the residues...
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