Mutations in the spacer peptide and adjoining sequences in Rous sarcoma virus Gag lead to tubular budding.

doi:10.1128/JVI.00213-08

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Article

Mutations in the spacer peptide and adjoining sequences in Rous sarcoma virus Gag lead to tubular budding.

Journal of virology - 1 Jul 2008

Keller Paul W, Johnson Marc C, Vogt Volker M

Abstract excerpt

All orthoretroviruses encode a single structural protein, Gag, which is necessary and sufficient for the assembly and budding of enveloped virus-like particles from the cell. The Gag proteins of Rous sarcoma virus (RSV) and human immunodeficiency virus type 1 (HIV-1) contain a short spacer peptide (SP or SP1, respectively) separating the capsid (CA) and nucleocapsid (NC) domains. SP or SP1 and the residues...

Topics

Amino Acid Sequence
Amino Acid Substitution
Animals
Cell Line
Chickens
Gene Products, gag
Genetic Complementation Test
HIV-1
Leukemia Virus, Murine
Microscopy, Electron, Scanning
Microscopy, Electron, Transmission
Molecular Sequence Data
Mutagenesis, Insertional
Mutation

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Identifiers

PMID: 18448521
DOI: 10.1128/JVI.00213-08
PMCID: PMC2446955

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Structure, Secondary

Recombination, Genetic

Rous sarcoma virus

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