Article
Association between H-ras minisatellite and colorectal cancer risk.
Anticancer research - 1 Jan 2000
Gosse-Brun S, Sauvaigo S, Daver A, Larra F, Kwiatkowski F, Bignon Y J, Bernard-Gallon D
Abstract excerpt
BACKGROUND: The H-ras locus has been suggested to play an important role in susceptibility to cancer. However, the results remain controversial. METHODS: In order to elucidate the potential role of the H-ras locus in colorectal carcinogenesis, 142 colorectal tumors with matched normal samples were studied for genomic instability and loss of heterozygosity (LOH), and 143 healthy samples of white blood cell DNA...
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