Association between MLH1 -93G>a polymorphism and risk of colorectal cancer.

doi:10.1371/journal.pone.0050449

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Article

Association between MLH1 -93G>a polymorphism and risk of colorectal cancer.

PloS one - 1 Jan 2012

Wang Ting, Liu Yang, Sima Li, Shi Liang, Wang Zhaoming, Ni Chunhui, Zhang Zhengdong, Wang Meilin

Abstract excerpt

BACKGROUND: The -93G>A (rs1800734) polymorphism located in the promoter of mismatch repair gene, MLH1, has been identified as a low-penetrance variant for cancer risk. Many published studies have evaluated the association between the MLH1 -93G>A polymorphism and colorectal cancer (CRC) risk. However, the results remain conflicting rather than conclusive. OBJECTIVE: The aim of this study was to assess the...

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PMID: 23226285
DOI: 10.1371/journal.pone.0050449
PMCID: PMC3511571

Genes

MLH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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