Analysis of Ha-ras 1 allele frequencies in hereditary non-polyposis colorectal cancer.

doi:10.1136/gut.36.3.382

Back to search

Article

Analysis of Ha-ras 1 allele frequencies in hereditary non-polyposis colorectal cancer.

Gut - 1 Mar 1995

Jeevaratnam P, Browett P J, Van de Water N S, Jass J R

Abstract excerpt

Restriction enzyme digests of genomic DNA show multiple alleles of common, intermediate, and rare frequencies at the minisatellite locus of Ha-ras. It has been suggested that a higher frequency of rare alleles is associated with the presence of colorectal and other types of cancer. This study inv...

Topics

Alleles
Colorectal Neoplasms, Hereditary Nonpolyposis
Gene Frequency
Genes, ras
Humans
In Situ Hybridization
Risk Factors

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.