Article
The human leukocyte antigen region and colorectal cancer risk.
Diseases of the colon and rectum - 1 Feb 2005
de Jong Mirjam M, Niens Marijke, Nolte Ilja M, te Meerman Gerard J, van der Graaf Winette T A, Mulder Marcel J, van der Steege Gerrit, Bruinenberg Marcel, Schaapveld Michael, Sijmons Rolf H, Hofstra Robert M W, de Vries Elisabeth G E, Kleibeuker Jan H
Abstract excerpt
PURPOSE: Recently, we found a certain haplotype in the human leukocyte antigen Class III subregion to be associated with breast cancer. Epidemiologic studies have shown that breast cancer and colorectal cancer have several risk factors in common. In view of these studies and because polymorphisms located in the human leukocyte antigen III region have been found to be associated with colorectal cancer, we wondered...
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