Article
Specific H-Ras minisatellite alleles in breast cancer susceptibility.
Anticancer research - 1 Jan 2000
Gosse-Brun S, Sauvaigo S, Daver A, Page M, Lortholary A, Larra F, Bignon Y J, Bernard-Gallon D
Abstract excerpt
Mutations in BRCA1 and BRCA2 genes account for the majority of familial aggregation of breast and ovarian cancers but other common genes in the population with low penetrance should be also involved in susceptibility to breast cancer. The H-ras minisatellite, located downstream of H-ras oncogene, is considered to be a likely candidate. Previous findings have estimated that as many as 1 in 11 cancers of the breast...
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