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Article

Apolipoprotein E genotype, atherosclerosis, and cognitive decline: the Rotterdam Study.

Journal of neural transmission. Supplementum - 1 Jan 1998

Slooter A J, van Duijn C M, Bots M L, Ott A, Breteler M B, De Voecht J, Wehnert A, de Knijff P, Havekes L M, Grobbee D E, Van Broeckhoven C, Hofman A

Abstract excerpt

The apolipoprotein E4 allele (APOE epsilon 4) and atherosclerosis are risk factors for cognitive decline. We investigated whether the effects of APOE epsilon 4 and atherosclerosis on cognitive decline are independent. A population-based follow-up study was performed on 838 subjects who were non-demented at baseline. The Mini Mental State Examination (MMSE) score at follow-up was studied as a function of APOE...

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Identifiers

PMID: 9700643
DOI: 10.1007/978-3-7091-6467-9_3

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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