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Article

Cerebrovascular disease, APOE epsilon4 allele and cognitive decline in a cognitively normal population.

Neurological research - 1 Sept 2006

Qiu Chengxuan, Winblad Bengt, Fratiglioni Laura

Abstract excerpt

OBJECTIVES: To investigate whether cerebrovascular disease (CVD) and apolipoprotein E (APOE) epsilon4 allele were associated with cognitive decline and whether the relationship between CVD and cognitive decline varied by APOE epsilon4 status. METHODS: A total of 809 cognitively normal community-dwelling residents aged >75 years were followed to detect subjects with cognitive decline, defined as follow-up....

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Source

Identifiers

PMID: 16945218
DOI: 10.1179/016164106X130443

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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