Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers.

doi:10.1006/gyno.1998.5039

Back to search

Article

Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers.

Gynecologic oncology - 1 Jul 1998

Maxwell G L, Risinger J I, Tong B, Shaw H, Barrett J C, Berchuck A, Futreal P A

Abstract excerpt

OBJECTIVE: The PTEN tumor suppressor gene on chromosome 10q23 undergoes inactivating mutations in several types of malignancies including glioblastomas and prostate and endometrial carcinomas. The aim of this study was to determine if mutation of the PTEN tumor suppressor gene is a feature of spo...

Topics

Exons
Female
Genes, Tumor Suppressor
Humans
Mutation
Ovarian Neoplasms
PTEN Phosphohydrolase
Phosphoric Monoester Hydrolases
Protein Tyrosine Phosphatases
Tumor Suppressor Proteins

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.