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Article

Homozygous deletion of the PTEN tumor-suppressor gene is not a feature in oral squamous cell carcinoma.

Oral oncology - 1 Jan 2000

Chen Q, Samaranayake L P, Zhou H, Xiao L

Abstract excerpt

A recently identified putative tumor-suppressor gene, PTEN, at 10q23 has been described as mutated or homozygously deleted in many different human tumors. To determine the role of the homozygous deletion of this PTEN gene in oral squamous cell carcinoma (OSCC), we screened two cell lines derived from the latter tissue and 28 tumor samples from patients with OSCC, using a differential display polymerase chain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10889927
DOI: 10.1016/s1368-8375(99)00068-8

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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