Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of mutation and expression of PTEN gene mRNA on tumorigenesis and progression of epithelial ovarian cancer.

Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 1 Mar 2004

Chen Ying, Zheng Huachuan, Yang Xuefei, Sun Limei, Xin Yan

Abstract excerpt

OBJECTIVE: To investigate the mutation and expression of tumor suppressor gene-PTEN mRNA and explore their roles in tumorigenesis and progression of ovarian cancer. METHODS: Mutated exon 5 of PTEN gene was examined in normal ovary (n=5), ovarian cyst (n=5), ovarian borderline tumor (n=9), epithelial ovarian cancer (n=60), and ovarian cancer cell line (n=1) by polymerase chain reaction-single strand conformation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Endometrioid
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Ovarian Neoplasms

Share to Phosphoric Monoester Hydrolases

Share to Polymorphism, Single-Stranded Conformational

Share to PTEN Phosphohydrolase

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 15104221

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of mutation and expression of PTEN gene mRNA on tumorigenesis and progression of epithelial ovarian cancer.PMID 15104221Read ↗

[Study of the mutation and expression of PTEN gene in endometrial carcinoma and epithelial ovarian cancer].Semantic proximity Read ↗

PTEN expression and mutation in colorectal carcinomas.Semantic proximity Read ↗

[Detection of mutation and protein expression of PTEN gene in endometrial carcinoma].Semantic proximity Read ↗

[Research on the mechanisms of PTEN gene inactivation in ovarian cancer].Semantic proximity Read ↗

A comprehensive analysis of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) loss in colorectal cancerSemantic proximity Read ↗

PTEN and Gynecological CancersSemantic proximity Read ↗

Mutational and expressional analyses of PTEN gene in colorectal cancer from Northern India.Semantic proximity Read ↗

PTEN mutation, expression and LOH at its locus in ovarian carcinomas. Relation to TP53, K-RAS and BRCA1 mutations.Semantic proximity Read ↗

In Vitro and In Vivo Effects of Tumor Suppressor Gene PTEN on Endometriosis: An Experimental StudySemantic proximity Read ↗

Possible relevance of tumor-related genes mutation to malignant transformation of endometriosis.Semantic proximity Read ↗

Role of exon 7 PTEN Gene in Endometrial Carcinoma.Semantic proximity Read ↗

PCR-SSCP-DNA sequencing method in detecting PTEN gene mutation and its significance in human gastric cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.