Article
Single mutations of the PTEN gene in recurrent ovarian carcinomas.
Journal of the Society for Gynecologic Investigation - 1 Jan 2000
Schöndorf T, Dostal A, Grabmann J, Göhring U J
Abstract excerpt
OBJECTIVE: To establish the role of phosphate and tensin homologue on chromosome 10 (PTEN) mutations in tumorigenesis of the ovary, we determined the mutational spectrum of the PTENgene in surgical specimens of ovarian carcinomas. METHODS: The study group consisted of 86 ovarian cancer specimens...
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