Article
Response of the timeless protein to light correlates with behavioral entrainment and suggests a nonvisual pathway for circadian photoreception.
Neuron - 1 Jul 1998
Yang Z, Emerson M, Su H S, Sehgal A
Abstract excerpt
The period (per) and timeless (tim) genes are required for circadian behavioral rhythms in Drosophila. The current model for how these rhythms entrain to light is based upon the light induced decrease in timeless protein (TIM) levels. We show here that the TIM response to light correlates with th...
Topics
- Animals
- Behavior, Animal
- Calcium Channels
- Circadian Rhythm
- Dose-Response Relationship, Radiation
- Drosophila
- Drosophila Proteins
- Eye Abnormalities
- Eye Proteins
- Insect Proteins
- Light
- Mutation
- Neurons
- Photoreceptor Cells, Invertebrate
- Reference Values
- Rhodopsin
- TRPC Cation Channels