Article
Suppression of PERIOD protein abundance and circadian cycling by the Drosophila clock mutation timeless.
The EMBO journal - 15 Aug 1995
Price J L, Dembinska M E, Young M W, Rosbash M
Abstract excerpt
The timeless mutation (tim) leads to loss of circadian behavioral rhythms in Drosophila melanogaster. The effects of tim on rhythmicity involve interactions with period (per), a second essential clock gene, as the tim mutation suppresses circadian oscillations of per transcription and blocks nucl...
Topics
- Animals
- Biological Clocks
- Circadian Rhythm
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation
- Genes, Insect
- Light
- Mutation
- Nuclear Proteins
- Period Circadian Proteins
- Phosphorylation
- Photoperiod
- RNA Processing, Post-Transcriptional
- Suppression, Genetic