Article
Role of molecular oscillations in generating behavioral rhythms in Drosophila.
Neuron - 1 Feb 2001
Yang Z, Sehgal A
Abstract excerpt
Circadian oscillations of clock gene products are thought to provide time-of-day signals that drive overt rhythms. In Drosophila, RNA and protein levels of the period and timeless genes oscillate and the proteins autoregulate their transcription. To test the relevance of these oscillations, we expressed period and timeless under control of constitutively active promoters. Constitutive expression of either RNA...
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