The relA/spoT-homologous gene in Streptomyces coelicolor encodes both ribosome-dependent (p)ppGpp-synthesizing and -degrading activities.

doi:10.1128/JB.180.16.4123-4132.1998

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Article

The relA/spoT-homologous gene in Streptomyces coelicolor encodes both ribosome-dependent (p)ppGpp-synthesizing and -degrading activities.

Journal of bacteriology - 1 Aug 1998

Martínez-Costa O H, Fernández-Moreno M A, Malpartida F

Abstract excerpt

Streptomyces coelicolor (p)ppGpp synthetase (Rel protein) belongs to the RelA and SpoT (RelA/SpoT) family, which is involved in (p)ppGpp metabolism and the stringent response. The potential functions of the rel gene have been examined. S. coelicolor Rel has been shown to be ribosome associated, a...

Topics

Anthraquinones
Anti-Bacterial Agents
Cloning, Molecular
Escherichia coli
Genetic Complementation Test
Ligases
Mutation
Phenotype
Ribosomes
Sequence Homology
Streptomyces

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