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Article

The global role of ppGpp synthesis in morphological differentiation and antibiotic production in Streptomyces coelicolor A3(2).

Genome biology - 1 Jan 2007

Hesketh Andrew, Chen Wenqiong Joan, Ryding Jamie, Chang Sherman, Bibb Mervyn

Abstract excerpt

BACKGROUND: Regulation of production of the translational apparatus via the stringent factor ppGpp in response to amino acid starvation is conserved in many bacteria. However, in addition to this core function, it is clear that ppGpp also exhibits genus-specific regulatory effects. In this study we used Affymetrix GeneChips to more fully characterize the regulatory influence of ppGpp synthesis on the biology of...

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Identifiers

PMID: 17683547
DOI: 10.1186/gb-2007-8-8-r161
PMCID: PMC2374992

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CDA

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Source receipt: pubmed, retrieved 7 Sept 2026.

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