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Article

Two relA/spoT homologous genes are involved in the morphological and physiological differentiation of Streptomyces clavuligerus.

Microbiology (Reading, England) - 1 May 2004

Jin Wook, Ryu Yong Gu, Kang Sung Gyun, Kim Sung Keun, Saito Natsumi, Ochi Kozo, Lee Sang Hee, Lee Kye Joon

Abstract excerpt

This study is focused on the involvement of the unusual nucleotide (p)ppGpp during the morphological and physiological differentiation of Streptomyces clavuligerus. In particular, the functional and structural elements of two genes encoding the proteins RelA and Rsh were identified. The relA gene encodes an 843 aa protein (RelA), while the rsh gene encodes a 738 aa protein (Rsh). The relA and rsh genes were...

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PMID: 15133110
DOI: 10.1099/mic.0.26811-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Two relA/spoT homologous genes are involved in the morphological and physiological differentiation of Streptomyces clavuligerus.PMID 15133110Read ↗

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The relA/spoT-homologous gene in Streptomyces coelicolor encodes both ribosome-dependent (p)ppGpp-synthesizing and -degrading activities.Semantic proximity Read ↗

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