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Three gene products govern (p)ppGpp production by <i>Streptococcus mutans</i>

22 Aug 2007

Abstract excerpt

The current dogma implicating RelA as the sole enzyme controlling (p)ppGpp production and degradation in Gram-positive bacteria does not apply to Streptococcus mutans. We have now identified and characterized two genes, designated as relP and relQ, encoding novel enzymes that are directly involved in (p)ppGpp synthesis. Additionally, relP is co-transcribed with a two-component signal transduction system (TCS)....

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PMID: 17714452
DOI: 10.1111/j.1365-2958.2007.05897.x

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