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Article

PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers.

Oncogene - 30 Jul 1998

Yokomizo A, Tindall D J, Drabkin H, Gemmill R, Franklin W, Yang P, Sugio K, Smith D I, Liu W

Abstract excerpt

A putative tumor suppressor, PTEN/MMAC1 gene at 10q23 was recently identified and found to be mutated in many different human tumors. To determine the role of the PTEN/MMAC1 gene in lung cancer, we screened 34 small cell lung cancer (SCLC) cell lines, 10 SCLC tumors, 13 non-small cell lung cancer (NSCLC) cell lines and 10 NSCLC tumors using Denaturing HPLC (DHPLC) and direct sequencing methods. In SCLC, six (18%)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9696041
DOI: 10.1038/sj.onc.1201956

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers.PMID 9696041Read ↗

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PTEN Is a Potent Suppressor of Small Cell Lung CancerSemantic proximity Read ↗

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