Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue inhibitor of metalloproteinase (TIMP)-1 induces differentiation and an antiapoptotic phenotype in germinal center B cells.

Blood - 15 Aug 1998

Guedez L, Courtemanch L, Stetler-Stevenson M

Abstract excerpt

Tissue inhibitors of metalloproteinases (TIMPs) have been shown to be multifunctional factors. Contrasting with their enzyme-inhibitory activity, TIMPs also promote cell growth. Previously, we have reported an enhanced expression of TIMP-1 by normal reactive B cells and high-grade lymphomas. In the present study, a series of Burkitt's lymphoma (BL) cell lines were analyzed for their expression of TIMP-1. TIMP-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Cell Differentiation
Share to Herpesvirus 4, Human

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulin M

Share to Neoplasm Proteins

Share to Phenotype

Share to Recombinant Fusion Proteins

Share to Transfection

Source

Identifiers

PMID: 9694723

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue inhibitor of metalloproteinase (TIMP)-1 induces differentiation and an antiapoptotic phenotype in germinal center B cells.PMID 9694723Read ↗

Regulation of TIMP-1 phenotypic expression in Epstein--Barr virus-immortalized B lymphocytes.Semantic proximity Read ↗

An integrative analysis reveals the prognostic and immunological role of TIMP gene family in pan-cancerSemantic proximity Read ↗

The TIMP protein family: diverse roles in pathophysiologySemantic proximity Read ↗

Higher levels of TIMP-1 expression are associated with a poor prognosis in triple-negative breast cancerSemantic proximity Read ↗

Biological and Clinical Significance of TIMPs Expression in Breast Cancer: a Bioinformatic AnalysisSemantic proximity Read ↗

TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain.Semantic proximity Read ↗

Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancerSemantic proximity Read ↗

Whole Organism Profiling of the Timp Gene FamilySemantic proximity Read ↗

Myeloma Microenvironmental TIMP1 Induces the Invasive Phenotype in Fibroblasts to Modulate Disease Progression.Semantic proximity Read ↗

TFF1 antagonizes TIMP‐1 mediated proliferative functions in gastric cancerSemantic proximity Read ↗

TIMP-1 gene deficiency increases tumour cell sensitivity to chemotherapy-induced apoptosis.Semantic proximity Read ↗

Tissue inhibitor of matrix metalloproteinase-1 suppresses apoptosis of mouse bone marrow stromal cell line MBA-1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.