Back to search

Article

Biological and Clinical Significance of TIMPs Expression in Breast Cancer: a Bioinformatic Analysis

2023-06-21

Abstract excerpt

Tissue inhibitors of metalloproteinases (TIMPs) are essential players during tumor progression in various types of cancer, including breast cancer. TIMPs regulate the activity of matrix metallo-proteinases (MMPs) at different levels. However, a dual role for TIMPs in breast carcinogenesis, either promoting or inhibiting tumor progression, has been observed. By a comprehensive bioin-formatics analysis using differe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4c38c58e-6bec-5591-9870-29ac3414a9c3
DOI
10.20944/preprints202306.1524.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Biological and Clinical Significance of TIMPs Expression in Breast Cancer: a Bioinformatic AnalysisDOI 10.20944/preprints202306.1524.v1
A Comprehensive Bioinformatics Analysis of TIMP2 in Multiple MalignanciesSemantic proximity
Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancerSemantic proximity
Multi-omics Analysis and Functional Characterization of the TIMP1 in Colorectal CancerSemantic proximity
Higher levels of TIMP-1 expression are associated with a poor prognosis in triple-negative breast cancerSemantic proximity
An integrative analysis reveals the prognostic and immunological role of TIMP gene family in pan-cancerSemantic proximity
Polymorphisms in tissue inhibitors of metalloproteinases-2 and -3 and breast cancer susceptibility and survival.Semantic proximity
Tissue Inhibitor of Metalloproteinases-4. The road less traveledSemantic proximity
The TIMP protein family: diverse roles in pathophysiologySemantic proximity
TIMP-1 Increases Expression and Phosphorylation of Proteins Associated with Drug Resistance in Breast Cancer CellsSemantic proximity
Whole Organism Profiling of the Timp Gene FamilySemantic proximity
Landscape Analysis of Matrix Metalloproteinases Unveils Key Prognostic Markers for Patients With Breast CancerSemantic proximity
Identification of New Key Genes and Their Association with Breast Cancer Occurrence and Poor Survival Using In Silico and In Vitro MethodsSemantic proximity
Select a neighboring publication to make it the new centre.