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Article

TFF1 antagonizes TIMP‐1 mediated proliferative functions in gastric cancer

23 Jul 2018

Abstract excerpt

Tissue inhibitor matrix metalloproteinase-1 (TIMP1) is one of four identified members of the TIMP family. We evaluated the role of TIMP1 in gastric cancer using human and mouse tissues along with gastric organoids and in vitro cell models. Using quantitative real-time RT-PCR, we detected significant overexpression of TIMP1 in the human gastric cancer samples, as compared to normal stomach samples (P < 0.01). We...

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PMID: 30035371
DOI: 10.1002/mc.22880

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