Article
Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2).
Journal of bacteriology - 1 Dec 1996
Shima J, Hesketh A, Okamoto S, Kawamoto S, Ochi K
Abstract excerpt
A strain of Streptomyces lividans, TK24, was found to produce a pigmented antibiotic, actinorhodin, although S. lividans normally does not produce this antibiotic. Genetic analyses revealed that a streptomycin-resistant mutation str-6 in strain TK24 is responsible for induction of antibiotic synt...
Topics
- Alleles
- Amino Acid Sequence
- Anthraquinones
- Anti-Bacterial Agents
- Base Sequence
- DNA, Bacterial
- Drug Resistance, Microbial
- Glutamic Acid
- Lysine
- Molecular Sequence Data
- Point Mutation
- Ribosomal Proteins
- Sequence Homology, Amino Acid
- Streptomyces
- Streptomycin