Article
The fitness cost of streptomycin resistance depends on rpsL mutation, carbon source and RpoS (sigmaS).
Genetics - 1 Oct 2009
Paulander Wilhelm, Maisnier-Patin Sophie, Andersson Dan I
Abstract excerpt
Mutations that cause antibiotic resistance often produce associated fitness costs. These costs have a detrimental effect on the fate of resistant organisms in natural populations and could be exploited in designing drugs, therapeutic regimes, and intervention strategies. The streptomycin resistan...
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