Article
Rab6 regulation of rhodopsin transport in Drosophila.
The Journal of biological chemistry - 7 Aug 1998
Shetty K M, Kurada P, O'Tousa J E
Abstract excerpt
Rab6 is a GTP binding protein that regulates vesicular trafficking within the Golgi and post-Golgi compartments. We overexpressed wild-type, a GTPase defective (Q71L), and a guanine nucleotide binding defective (N125I) Rab6 protein in Drosophila photoreceptors to assess the in vivo role of Rab6 in the trafficking of rhodopsin and other proteins. Expression of Drab6(Q71L) greatly reduced the steady state levels of...
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