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Article

Phosphoinositides, ezrin/moesin, and rac1 regulate fusion of rhodopsin transport carriers in retinal photoreceptors.

Molecular biology of the cell - 1 Jan 2004

Deretic Dusanka, Traverso Valerie, Parkins Nilda, Jackson Fannie, Rodriguez de Turco Elena B, Ransom Nancy

Abstract excerpt

The post-Golgi trafficking of rhodopsin in photoreceptor cells is mediated by rhodopsin-bearing transport carriers (RTCs) and regulated by the small GTPase rab8. In this work, we took a combined pharmacological-proteomic approach to uncover new regulators of RTC trafficking toward the specialized light-sensitive organelle, the rod outer segment (ROS). We perturbed phospholipid synthesis by activating...

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Identifiers

PMID: 13679519
DOI: 10.1091/mbc.e03-04-0203
PMCID: PMC307553

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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