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Article

A role for rhodopsin in a signal transduction cascade that regulates membrane trafficking and photoreceptor polarity.

Vision research - 1 Dec 2006

Deretic Dusanka

Abstract excerpt

This review summarizes the most recent progress in the understanding of the role of rhodopsin C-terminal domain in the regulation of intracellular trafficking and photoreceptor morphogenesis. A proposed cascade of molecular interactions, initiated by the rhodopsin C-terminal sequence VXPX-COOH during trafficking from the Golgi/TGN in retinal photoreceptors, is relayed by the small GTPase ARF4 to the downstream...

Topics

Animals
Cell Membrane
Cell Polarity
Humans
Mutation
Neurodegenerative Diseases
Protein Structure, Tertiary
Protein Transport
Rhodopsin
Rod Cell Outer Segment
Vision, Ocular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17010408
DOI: 10.1016/j.visres.2006.07.028

Genes

ARF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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A role for rhodopsin in a signal transduction cascade that regulates membrane trafficking and photoreceptor polarity.PMID 17010408Read ↗

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