Article
The V-ATPase V1 subunit A1 is required for rhodopsin anterograde trafficking in Drosophila.
Molecular biology of the cell - 1 Jul 2018
Zhao Haifang, Wang Jing, Wang Tao
Abstract excerpt
Synthesis and maturation of the light sensor, rhodopsin, are critical for the maintenance of light sensitivity and for photoreceptor homeostasis. In Drosophila, the main rhodopsin, Rh1, is synthesized in the endoplasmic reticulum and transported to the rhabdomere through the secretory pathway. In an unbiased genetic screen for factors involved in rhodopsin homeostasis, we identified mutations in vha68-1, which...
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