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Article

Drosophila fabp is required for light-dependent Rhodopsin-1 clearance and photoreceptor survival.

PLoS genetics - 1 Oct 2021

Huang Huai-Wei, Ryoo Hyung Don

Abstract excerpt

Rhodopsins are light-detecting proteins coupled with retinal chromophores essential for visual function. Coincidentally, dysfunctional Rhodopsin homeostasis underlies retinal degeneration in humans and model organisms. Drosophila ninaEG69D mutant is one such example, where the encoded Rh1 protein imposes endoplasmic reticulum (ER) stress and causes light-dependent retinal degeneration. The underlying reason for...

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Identifiers

PMID: 34714826
DOI: 10.1371/journal.pgen.1009551
PMCID: PMC8580249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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