Article
The GTP- and Phospholipid-Binding Protein TTD14 Regulates Trafficking of the TRPL Ion Channel in Drosophila Photoreceptor Cells.
PLoS genetics - 1 Oct 2015
Cerny Alexander C, Altendorfer André, Schopf Krystina, Baltner Karla, Maag Nathalie, Sehn Elisabeth, Wolfrum Uwe, Huber Armin
Abstract excerpt
Recycling of signaling proteins is a common phenomenon in diverse signaling pathways. In photoreceptors of Drosophila, light absorption by rhodopsin triggers a phospholipase Cβ-mediated opening of the ion channels transient receptor potential (TRP) and TRP-like (TRPL) and generates the visual response. The signaling proteins are located in a plasma membrane compartment called rhabdomere. The major rhodopsin (Rh1)...
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