A G protein-coupled receptor phosphatase required for rhodopsin function.

doi:10.1126/science.277.5326.687

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Article

A G protein-coupled receptor phosphatase required for rhodopsin function.

Science (New York, N.Y.) - 1 Aug 1997

Vinós J, Jalink K, Hardy R W, Britt S G, Zuker C S

Abstract excerpt

Heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors are phosphorylated by kinases that mediate agonist-dependent receptor deactivation. Although many receptor kinases have been isolated, the corresponding phosphatases, necessary for restoring the ground state of the re...

Topics

Animals
Animals, Genetically Modified
Arrestin
Calcium-Binding Proteins
Darkness
Drosophila
Drosophila Proteins
Electroretinography
GTP-Binding Proteins
Light
Mutation
Phosphoprotein Phosphatases
Phosphorylation
Photoreceptor Cells, Invertebrate
Retina
Retinal Degeneration
Rhodopsin
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 9235891
DOI: 10.1126/science.277.5326.687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9235891-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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