Article
p53 gene mutation in the bone-marrow of a patient with diffuse mixed cell type lymphoma at diagnosis predicting eventual progression to large cell lymphoma.
Leukemia & lymphoma - 1 Apr 1998
Jhanwar-Uniyal M, Gulati S C
Abstract excerpt
Mutations of the p53 tumor suppressor gene have been used as molecular genetic markers of disease and serve as a prognostic indicator in various malignancies including non-Hodgkin's lymphoma (NHL). Alterations in the p53 gene were investigated in a bone marrow sample from a NHL patient admitted f...
Topics
- Antineoplastic Combined Chemotherapy Protocols
- Bone Marrow
- Cisplatin
- Dexamethasone
- Disease Progression
- Etoposide
- Fatal Outcome
- Genes, p53
- Genetic Markers
- Humans
- Ifosfamide
- Lymphoma, Large B-Cell, Diffuse
