Mutations of the p53 gene in B-cell lymphoblastic acute leukemia: a report on 60 cases.

Article

Mutations of the p53 gene in B-cell lymphoblastic acute leukemia: a report on 60 cases.

Leukemia - 1 Jan 1992

Fenaux P, Jonveaux P, Quiquandon I, Preudhomme C, Lai J L, Vanrumbeke M, Loucheux-Lefebvre M H, Bauters F, Berger R, Kerckaert J P

Abstract excerpt

Exons 5 to 8 of the p53 gene were examined for mutations in 60 patients with B-cell acute lymphoblastic leukemia (ALL), including 50 cases of precursor-B-cell ALL, nine cases of Burkitt (L3) ALL and one case of atypical ALL with surface immunoglobulins and t(8:14) translocation but L2 morphology....

Topics

Amino Acid Sequence
Burkitt Lymphoma
Exons
Female
Genes, p53
Humans
Male
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic

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